Human Body Orientation – Chapter 1

 

1.       (pg 3) Contrast :       Anatomy –the structure – descriptive; parts, shape, size

Physiology – the function of the structures

 

2.        List the levels of organization in order from the most complex to the least complex. (pg 4)

1.        Organism – the individual person

2.        Organ system

3.        Organ

4.        Tissues

5.        Cells

6.        Chemical (not a concern for this class)

 

3.        A group of specialized cells similar in function and origin is? A tissue

A group of tissues is? An organ

What is the study of tissues? Histology

What is the study of the transmission of disease? Epidemiology

What is the microscopic study of cells? Cytology

What is the sum of all chemical reactions in the body? Metabolism (controlled by thyroid)

 

4.       List 11 body systems and state the functions of these systems and the organs in these systems.

System

Function(pg 6-7)

Organs

Integumentary

External body covering (protection); protects deeper tissues; synthesizes vitamin D; site of cutaneous nerve receptors, sweat (temp. regulation), oil glands, get rid of waste products

Hair, skin, nails

Skeletal

Protects & supports body organs; provides framework for muscles to cause movement; blood cells are formed within; stores minerals

Bones, joints

Muscular

Locomotion; facial expression; maintain posture; produces heat

Skeletal muscles

Nervous

Fast acting control; regulator of function; responds to internal & external changes by activating muscles and glands

Brain, Sensory receptor, Spinal Cord, Nerves

Endocrine

Slower acting control; glands secrete hormones to regulate processes: growth, reproduction, metabolism by body cells

Pineal gland, pituitary gland, thyroid gland, parathyroid, thymus, adrenal gland, pancreas, ovary, testis

Cardiovascular

Transportation of blood; carries O2, CO2, nutrients, wastes, etc.; heart pumps blood

Heart, blood vessels

Lymphatic / Immunity

Picks up leaked fluid puts back into bloodstream; houses white blood cells (lymphocytes) – immune system

Thymus, lymphatic vessels, thoracic duct, spleen, lymph nodes, tonsils, red bone marrow

Respiratory

Keeps blood supplied with O2; removes CO2; through walls of air sacs in lungs

Nasal cavity, pharynx, larynx, trachea, lung, bronchus

Digestive

Breaks down food into absorbable units that enter blood for distribution to body cells; indigestible foodstuffs are eliminated as feces

Oral cavity, esophagus, stomach, small intestine, large intestine, rectum, anus, liver, gall bladder

Urinary

Eliminates nitrogenous wastes from body; regulates water, electrolyte, acid-base balance

Kidney, ureter, urinary bladder, urethra

Male Reproductive

Produce sperm, hormones; production of offspring; delivery to female reproductive system

Prostate gland, ductus deferens, scrotum, testis, penis

Female Reproductive

Produce eggs, female sex hormones; sites for fertilization, development of fetus; mammary glands produce milk for newborn

Mammary glands (in breasts), ovary, uterine tube, uterus, vagina

 

What system are the spleen, tonsils, and thymus in? Lymphatic system

What distributes oxygen and nutrients and carries away wastes? Cardiovascular

What system makes and matures most blood cells? Skeletal

What systems protect against disease? Lymphatic, Skeletal, cardiovascular, integumentary

What system returns protein and plasma to the blood stream? Lymphatic

What system eliminates liquid wastes and regulates fluid balance? Urinary

What system is made of glands that make hormones? Endocrine

What system contains hair, skin, and sweat glands? Integumentary

What system includes the liver and gall bladder? Digestive

What 2 systems regulate homeostasis? Endocrine, Nervous

What system supports and protects, stores minerals, and assists in body movements? Skeletal

 

5.       (pg 10)

Define homeostasis. The body’s ability to maintain relatively stable internal conditions even though the outside world changes continuously; constant internal environment.

List some factors that would disturb it. Anything that changes what you are doing, i.e. standing up.

The internal environment of the body is the extracellular fluid. True or False? But not all extracellular fluid; interstitial is between or around the cells, not blood; extracellular is outside the cell, includes the blood and interstitial fluid.

Does extracellular fluid include intracellular (inside the cell) fluid? NO

Homeostasis is regulated by what two systems? Endocrine, Nervous

Describe negative feedback. (pg 11) It causes a reduction or increase in the amount of a certain substance; increases when you want more; it causes the variable to change direction opposite to that of the initial change, returning it to its “ideal” value.

If negative feedback were operating in the body (which it usually is for most processes) and NaCl concentration is lowered, the body would raise the NaCl in response. (pg 13)

If positive feedback was operating in the body (which it usually is not for most processes), and the NaCl concentration is lowered, the body would lower the NaCl. (pg 13) Childbirth example

 

6.       Describe anatomical position. (pgs 15 & 16)

 

Term

Definition

Example

Superior (cranial)

Toward the head end or upper part of the body; above

The head is superior to the abdomen.

Inferior (caudal)

Away from the head end or toward the lower part of the body; below

The navel is inferior to the chin.

Anterior (ventral)

Toward or at the front of the body; in front of

The breastbone is anterior to the spine.

Posterior (dorsal)

Toward or at the back of the body; behind

The heart is posterior to the breastbone.

Medial

Toward or at the midline of the body; on the inner side of

The heart is medial to the arm.

Lateral

Away from the midline of the body; on the outer side of

The arms are lateral to the chest.

Proximal

Closer to the origin of the body part or the point of attachment of a limb to the body trunk

The elbow is proximal to the wrist.

Distal

Farther from the origin of a body part or the point of attachment of a limb to the body trunk

The knee is distal to the thigh.

Superficial

Toward or at the body surface

The skin is superficial to the skeletal muscles.

Deep

Away from the body surface; more internal

The lungs are deep to the skin.

 

The stomach is inferior to the heart. The elbow is distal / inferior to the shoulder. The sternum is anterior / superficial to the heart. The spinal cord is posterior to the heart. The cheeks are lateral to the nose, superior / medial to the arm, and superior / lateral to the navel.

 

7.      

Frontal Plane

 
(pgs 15 & 17)

                                                            

 

 

 

 

 

 

 

 

 


What planes of section produce a top and bottom half?  Transverse; Horizontal; Cross section

A left and right?  Median (midsagittal); sagittal; parasagittal (not directly on the midline)

A front and back? Frontal Planes; Coronal

An inferior and superior?  Cross Section; Transverse; Horizontal

A medial and lateral? Sagittal; Median

An anterior and posterior? Frontal

 


8.       Locate and name the organs and the coverings of the organs in the: (pgs 18, 19)

Ventral Body Cavities

Organs

Coverings

Mediastinum (thoracic)

Heart (anterior)

Visceral pericardium

Parietal pericardium

Trachea; Esophagus (posterior)

Pleural cavity (thoracic)

Lungs

Visceral pleura

Parietal pleura

Pericardial Cavity (thoracic)

Heart (anterior)

Visceral pericardium

Parietal pericardium

Abdominal cavity

Stomach; pancreas; intestines; spleen; liver; kidneys; etc.

Visceral peritoneum

Parietal peritoneum

Pelvic Cavity

Reproductive organs; bladder; rectum

Visceral peritoneum

Parietal peritoneum

       Visceral (on an organ)                    There is an imaginary line between the Abdomen and Pelvic Cavities

Parietal (lining a cavity)

 

Most of the mediastinum is between (medial to) what two body cavities? Pleural cavities

The posterior mediastinum is posterior to what cavity? Pericardial cavity

 

Chemistry – Chapter 2: pages 44 & 69

 

Mole -quantity of a chemical substance in grams; weight in grams that equals the molecular weight in a liter of solution

                Na = 23 gr. (Periodic Table)      1 mole of NaCl = 58 grams of NaCl

                Cl = 35 gr.

pH = acid = H+      pH Scale = 1 to 14 ; 7 is neutral

 

If pH = 5 there is 10-5 moles of H+ per liter

              there are 10-9 moles of OH- per liter

If pH = 12 there is 10-12 moles of H+ per liter

                 there are 10-2 moles of OH- per liter

The larger the pH the less acidic the solution

At 7 pH – same amount of H+ as OH-

PH of Blood about 7.35 – 7.45

 

Acid – a substance that releases hydrogen ions (H+)

Base – proton acceptors; a substance that takes up hydrogen ions (H+)

 

(pgs 43, 44)

9.       How many moles of H+ per liter are there in a solution with a pH of 4? 10–4 moles of H+

What is the concentration of OH- in moles per liter? 10-10 moles of OH-

      A solution with a pH of 7.5 is more or less acidic than a pH solution of 7.4?

      A solution with a pH of 7.5 has more or less H+ than the solution with a pH of 7.4?

 

10.   (pgs 55,53)Denaturing a protein results in? unfolding of the 3-D structure; destruction of protein

Proteins are made where? ribosomes

Most enzymes are made of what? Proteins; amino acids

What may permanently alter proteins? High temperatures; drop in pH

What is this alteration called? Denaturation

Proteins are the main functional part of the cell membrane – True or False? (pg 69)

 


Cells -  Chapter 3: pages 66, 67, etc.

11.   Describe the function and or composition of: (pg 66-67)

Cell Part

Function

Composition

Mitochondria

Synthesizes ATP for energy

Sausage or cigar shaped

Lysosomes

Digestion of cell parts; bacteria; viruses

Acid hydrolases, large sacs

Golgi Apparatus

Packages, modifies, segregates proteins for secretion, storage into lysosomes

 

Endoplasmic Reticulum

Coils through cytoplasm, divides cytoplasm into channels; location of most ribosomes

 

Nucleus

Controls cell

Contains Chromatin and nucleolus

Nucleolus

Houses RNA inside nucleus

Ribosomal RNA, encompasses DNA

Ribosomes

Site of protein synthesis

RNA; protein

Cell Membrane

Transportation; “gatekeeper”; barrier

Proteins; double phospholipids

Genes

Blueprint for proteins;

DNA sequences

Chromatin

DNA; genes

Thin strings  DNA; interphase DNA

Chromosomes

DNA; life blue print

Short bar like; formed in prophase

Centrioles

During mitosis form spindle and asters; bases of cilia, flagella

Paired cylindrical bodies; nine triplets of microtubules

Cilia

Create current to move items across cell

Centrioles; Respiratory & reproductive systems

Flagella

Used to propel a cell

Longer cilia; human sperm tail

The selective permeability of the cell membrane depends on what several factors?

1.        Soluble in Lipid (fat); simple diffusion; dissolving into cell membrane; O2, CO2 (pg 73)

2.        Size – can it go through the “doors”; usually only small things

3.        Charge on the substance; outside of cell is positive; inside of cell is negative (pg 81)

An electrical gradient or membrane potential exists in the cell membrane because the inside of the membrane is negative relative to the outside. (pg 81)

How many genes are there in a cell? thousands

What transcribes genes in the first step of protein synthesis? Messenger RNA from Nucleolus

Protein synthesis takes place where? Ribosomes (pg 102)

What digests old organelles? lysosomes

What do Golgi and mitochondria look like? Stacks of pancakes or pita bread; hot dog or cigar shaped

What is the difference between cilia and flagella?

                  Cilia – small; moves things across cell

                        Flagella – long cilia; causes motion of entire cell

Where are they found?

                  Cilia – surface of cell membrane; respiratory & reproductive systems

                        Flagella – human sperm

 

12.     Describe crenation and hemolysis. (pg 74,75) In Red Blood Cells

Crenation – loss of water; shrink; in hypertonic solution

Hemolysis – gain of water; bloat; burst; in hypotonic solution

In what situation would these processes occur?

                  Hypertonic Solution – crenation

                        Hypotonic Solution – hemolysis

                        Isotonic Solution – cells stay the same size; no change; equal solution

List two passive methods by which substances enter or exit from the cell. Diffusion; Osmosis

Do passive processes require energy? NO

Do active processes require energy? YES

Does the process of osmosis require a membrane? YES

What kind of membrane? SELECTIVELY PERMEABLE

Is it the movement of any substance? NO

Any liquid? No, water!

Is osmosis an active or passive process? passive

Contrast phagocytosis and pinocytosis?   Phagocytosis –  large solids taken into the cell

                                                                                 Pinocytosis – large amounts of liquids taken into the cell

 

13.   If there is no net movement across a membrane separating 2 solutions, these solutions are isotonic to each other.

When substances move down a concentration gradient (from high to low concentration), this process is diffusion.

If substances move the other direction (from low concentration to high), this process is called active transport.

Which process would require energy? Active transport

Which process is active? Active transport

Perfume moves from the bathroom to the living room by what process? Diffusion

 

14.   If “A” has more solutes (and less water) than ‘B’. ‘A’ is hypertonic to ‘B’.

Which has the higher osmotic pressure? Solution ‘A’ with 10% NaCl or Solution ‘B’ with 20%NaCl.

Why? More NaCl has more (higher) osmotic pressure; the higher the salt the higher the osmotic pressure

‘B’ is what relative to ‘A’? hypertonic or hypotonic

‘A’ is what relative to ‘B’? hypertonic or hypotonic

 

 

 

 

 

 

 

 

 

 

 

 


Osmotic Pressure – solution with the most salt – where the water is going (pg 75)

Name of the solution that the cell is in tells “how much salt is in the solution”

 

15.   If a red blood cell, 10% NaCl, is placed in a 1% NaCl solution, the cell will shrink, swell, or stay the same?

What is the change called? hemolysis

The 1% solution would be hypotonic, hypertonic or isotonic?

If a cell is 10% NaCl and is placed in a 90% NaCl solution, would the cell shrink, swell, or stay the same? shrink

Why? Water diffuses out of the cell into the solution

What is this change called? crenation

Is the solution hypotonic, hypertonic, or isotonic?

If the same cell were placed in a 10% NaCl solution, what change would you observe? None

The solution would be what relative to the cell? Isotonic

 


Cell Division – Mitosis and Meiosis – Chapter 3 pg 97

 

Mitosis: Prophase:

1.       chromosomes appear / form from Chromatin

2.       Nucleoli Disappear

3.       Mitotic Spindle forms – Centrioles separate

4.       Nuclear membrane disappears

Metaphase:

1.       Chromosomes cluster in the middle of cell

Anaphase:

1.       Centromeres of chromosome split

2.       Chromatids are separated

Telophase: (reverse of Prophase)

1.       Chromosomes form Chromatin

2.       Spindle disappears

3.       Nucleoli Appear

4.       Nuclear Membrane forms

5.       Cleavage Furrow forms – Cytokinesis begins

Mitosis

Meiosis

1. growth and repair

1. egg and sperm production

2. asexual reproduction

2. sexual reproduction

3. 1 cell produces 2 cells; one series of steps

3. 1 cell produces 4 cells; two series of steps

4. cells produced are identical to the original

4. cells produced are not identical to the original

5. cells produced have the same number of chromosomes as the original cell; diploid to diploid; haploid to haploid

5. cells produced have half the number of chromosomes as the original cell; diploid to haploid

6. chromatids separate

6. Meiosis I – homologous pairs separate;                                                          Meiosis II – chromatids separate

 

16.   List the stages of mitosis in order. (pg 97)

PMAT:   Prophase

Metaphase

Anaphase

Telophase

Which is longer – interphase or mitosis? When cells are not dividing; DNA is in chromatin form

During what stage of mitosis do these events occur?

Centrioles move apart – Prophase

Nucleoli disappear – Prophase

Chromatid pairs separate – Anaphase

Chromosomes line up at the equator of the cell – Metaphase

Cytokinesis begins – Telophase

 

17.   Define cytokinesis. The pinching of the cell membrane to complete the physical division of a cell.

Cytokinesis begins with the formation of what? The cleavage furrow

 

18.   The union of gametes is called what? Fertilization

Chromosomes do not double with each generation because of meiosis.  Sex cells have half the chromosomes

Diploid has two sets of chromosomes or one set? Two sets

Haploid has two sets of chromosomes or one? One set

 


19.   Compare the end result of mitosis and meiosis. (pg 1077)

Mitosis – one cell becomes 2 new cells like original

Meiosis – one cell becomes 4 sex cells (gametes); not like original; not identical; half the chromosomes

Which process occurs in two series of steps? Meiosis

Which process only requires only one series of steps? Mitosis

Which process is described in the following?

Diploid to Diploid – mitosis

Diploid to haploid – meiosis

Haploid to haploid – mitosis (in plants)

Haploid to diploid – fertilization

Which cell has 23 chromosomes: gametes, sperm, oocyte, skin cell, liver, and muscle cells?

What is the function of mitosis? Growth; repair

Meiosis? Egg & sperm production; sexual reproduction

Which process occurs in most cells of the body? Mitosis

Which process occurs only in the ovary and testes? Meiosis

Egg production is called? Oogenesis

Sperm production is called? Spermatogenesis

 

20.   An increase in size of an organ due to an increase in mitosis (in the number of cells) is called?

Hyperplasia - Cancer

An increase in the size of an organ due to an increase in the size of the cells is called?

                  Hypertrophy – swelling or working out muscles with exercise